It is just a mind game to satisfy scientists - theoretical physicists.
First, considering Bostroms A, B, C - A 33.3% chance we are in a Sim - does not require humans... or even anything in our galaxy/universe. Why? Why would humans be required? Why couldn't non-humans create an experimental Sim that is a "simularium" and we just evolved in it? what if "we" are their attempt an a sentient Ai?